![]() In addition, over the last decade, new challenges have arisen such as increasingly complicated recipients and antibody-mediated rejection. ![]() This is mainly due to chronic rejection, malignancy, and the detrimental side effects of chronic immunosuppression. However, there has been little change in long-term outcomes. The 1-yr survival rates following heart transplantation have improved from 30% in the 1970s to almost 90% in the 2000s. ![]() ![]() There has been significant progress in the field of heart transplantation over the last 45 years. ![]()
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